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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 22.42
Human Site: S891 Identified Species: 32.89
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 S891 L E N S L R Q S K A S C A D M
Chimpanzee Pan troglodytes XP_518055 1227 139177 S884 L E N S L R Q S K A S C A D M
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S891 L E S S L K Q S K T S C A D M
Dog Lupus familis XP_549061 1234 139874 N892 L E S S L K Q N K A S C A D M
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 S892 L E S S L N Q S K A S C I D V
Rat Rattus norvegicus Q7M6Z5 1394 158861 K966 K E A L L Q E K S H L E N K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 S895 L E S S L Q Q S K T N C S D I
Frog Xenopus laevis Q91784 1226 138905 N893 L E S S V K Q N R A H V A D L
Zebra Danio Brachydanio rerio Q58G59 1363 154819 T984 A L S Q D L L T L S S R I E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 L474 V R G G K N L L D T Y S E R Q
Honey Bee Apis mellifera XP_395595 1064 123475 I748 I E I L I S T I D A E Y S L E
Nematode Worm Caenorhab. elegans P46873 699 78760 N389 E E F E E A M N D L R G E Y E
Sea Urchin Strong. purpuratus P46872 699 78679 S389 E E S G S E E S G D E E A G E
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 S735 G N G A N G Q S N E K S L Q R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 S857 S T L V S M A S Q L S E A E E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 G618 E K L V E T Q G F V R Q A E L
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 80 80 N.A. 73.3 13.3 N.A. N.A. 60 46.6 6.6 N.A. 0 13.3 6.6 20
P-Site Similarity: 100 100 93.3 100 N.A. 86.6 26.6 N.A. N.A. 93.3 86.6 33.3 N.A. 6.6 33.3 13.3 33.3
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 13.3 N.A. N.A. 20 N.A. 13.3
P-Site Similarity: 20 N.A. N.A. 33.3 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 7 0 7 7 0 0 38 0 0 50 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 38 0 0 0 % C
% Asp: 0 0 0 0 7 0 0 0 19 7 0 0 0 44 0 % D
% Glu: 19 69 0 7 13 7 13 0 0 7 13 19 13 19 25 % E
% Phe: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 7 0 13 13 0 7 0 7 7 0 0 7 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % H
% Ile: 7 0 7 0 7 0 0 7 0 0 0 0 13 0 7 % I
% Lys: 7 7 0 0 7 19 0 7 38 0 7 0 0 7 7 % K
% Leu: 44 7 13 13 44 7 13 7 7 13 7 0 7 7 13 % L
% Met: 0 0 0 0 0 7 7 0 0 0 0 0 0 0 25 % M
% Asn: 0 7 13 0 7 13 0 19 7 0 7 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 13 57 0 7 0 0 7 0 7 7 % Q
% Arg: 0 7 0 0 0 13 0 0 7 0 13 7 0 7 7 % R
% Ser: 7 0 44 44 13 7 0 50 7 7 44 13 13 0 7 % S
% Thr: 0 7 0 0 0 7 7 7 0 19 0 0 0 0 0 % T
% Val: 7 0 0 13 7 0 0 0 0 7 0 7 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _